Yazar "Erbaş O." için listeleme
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Adipose-derived mesenchymal stem cells mitigate methotrexate-induced liver cirrhosis (fibrosis) model
OBJECTIVE: Hepatic fibrosis is a severe liver condition characterized by abnormal fibroblast activity, excessive extracellular matrix deposition, inflammation, and structural alterations. Methotrexate (MTX), a pharmaceutical ... -
Beneficial effects of sennoside B on pentylenetetrazole-induced seizures in rats
Background: Epilepsy is a common disorder affecting approximately 50 million people worldwide. Oxidative stress is known to play an important role in the pathophysiology of diseases, including epilepsy. In this study, we ... -
Demonstration of ameliorating effect of papaverine in sepsis-induced acute lung injury on rat model through radiology and histology
Özkul B.; Sever İ.H.; Yiğittürk G.; Elgörmüş Ç.S.; Gür S.G.; Erbaş O. (Turkish Association of Trauma and Emergency Surgery, 2023)BACKGROUND: Our target was to show the role of high mobility group box-1/receptor for (HMGB1/RAGE) interaction in feces intraperitoneal injection procedure (FIP)-induced acute lung injury (ALI) pathophysiology, to investigate ... -
The Effect of Liraglutide on Axon Regeneration and Functional Recovery after Peripheral Nerve Lesion
Yalçın M.B.; Bora E.S.; Erbaş O. (Multidisciplinary Digital Publishing Institute (MDPI), 2024)Peripheral nerve injuries inflict severe consequences, necessitating innovative therapeutic strategies. This study investigates the potential of liraglutide, a glucagon-like peptide-1 receptor agonist, in mitigating the ... -
Evaluation of the Reparative Effect of Sinomenine in an Acetaminophen-Induced Liver Injury Model
Kayalı A.; Bora E.S.; Acar H.; Erbaş O. (Multidisciplinary Digital Publishing Institute (MDPI), 2024)Due to its rising global prevalence, liver failure treatments are urgently needed. Sinomenine (SIN), an alkaloid from sinomenium acutum, is being studied for its liver-repair properties due to Acetaminophen (APAP) overdose. ... -
Oxytocin mitigates peripheral nerve damage via Nrf2 and irisin pathway
Tosyali H.K.; Bora E.S.; Çinaroğlu O.S.; Erbaş O. (Verduci Editore s.r.l, 2023)OBJECTIVE: Peripheral nerve injuries present challenges in achieving full functional restoration, necessitating effective therapeutic strategies. Oxytocin, known for its neuroprotective and anti-inflammatory properties, ... -
Short-term protective effect of octreotide on the lungs of rats with experimentally induced sepsis
Bora E.S.; Erdoğan A.; Erdoğan M.A.; Yigitturk G.; Çakır A.; Erbaş O. (Turkish Association of Trauma and Emergency Surgery, 2022)BACKGROUND: Acute respiratory distress syndrome is a devastating complication of severe sepsis. Preclinical models suggest that direct lung injury begins with attack to the lung epithelium, but indirect lung injury results ... -
Therapeutic Effects of Liraglutide, Oxytocin and Granulocyte Colony-Stimulating Factor in Doxorubicin-Induced Cardiomyopathy Model: An Experimental Animal Study
Taşkıran E.; Erdoğan M.A.; Yiğittürk G.; Erbaş O. (Humana Press Inc., 2019)Doxorubicin-induced (DXR) cardiomyopathy is a serious health issue in oncology patients. Effective treatment of this clinical situation still remains to be discovered. In this experimental animal study, we aimed to define ...